indazole-3-carboxamide - An Overview

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The artificial utility was also demonstrated by carrying out a gram-scale synthesis of 3a through the response of 1a with 2a underneath our optimized reaction ailments, which furnished 3a in 65% isolated yield (Plan two).

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, OCH3) groups was subjected to reaction with 1a beneath the optimized ailments; 3d was afforded in a little reduce (seventy eight%) produce in comparison to 3a and 3c. This could be because of the steric hindrance created through the OCH3 group on the o

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have been applied as prospective kinase inhibitors as is possible treatment for cancer. Indazole derivatives possess a wide array of pharmacological things to do such as antibacterial, antifungal, anti-inflammatory, anti-HIV, anti-arrhythmic and anti-tumor.32–37 The goal of this review will be to compile the work performed by distinct investigation groups in the sector of indazole derivatives as kinase inhibitors.

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